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Growth Factors Vis-A-Vis Healing of Bones

Growth Factors Vis-A-Vis Healing of Bones PDF Author: Shyamal Kanti Guha
Publisher: LAP Lambert Academic Publishing
ISBN: 9783848431526
Category :
Languages : en
Pages : 168
Book Description
The study of bone fracture and healing is a very challenging job in orthopedic surgery. In the present perspective of this endeavor is to document of ever increasing growth factors and their respective roles to get a successful repaired bone. Therefore the present study envisage the healing of bone fractures and the role of growth factors like TGF-ß1, IGF-1, FGF, PDGF, VEGF and bone morphogenetic proteins-2 and 7 in healing mechanism. In this book a comparative efficacy of TGF- 1, IGF-1 and the combined application of TGF- 1 and IGF-1 was evaluated in augmentation of segmental bone healing. We observed that the combined application of TGF- 1 and IGF-1 stimulated the production of osteoblasts that transformed into osteocytes produced synergistic osteoinductive effect in augmentation of fracture healing and remodeling process in combo group as compared to apply singly. I want to express my sincere wishes to Dr. S. Sarkar and Prof. Subhashis Biswas for their inspiring attitude that increased the strength for such work. Finally I want to express my sincere gratitude to my wife Sipra and son Himanish for their constant support.

Growth Factors Vis-A-Vis Healing of Bones

Growth Factors Vis-A-Vis Healing of Bones PDF Author: Shyamal Kanti Guha
Publisher: LAP Lambert Academic Publishing
ISBN: 9783848431526
Category :
Languages : en
Pages : 168
Book Description
The study of bone fracture and healing is a very challenging job in orthopedic surgery. In the present perspective of this endeavor is to document of ever increasing growth factors and their respective roles to get a successful repaired bone. Therefore the present study envisage the healing of bone fractures and the role of growth factors like TGF-ß1, IGF-1, FGF, PDGF, VEGF and bone morphogenetic proteins-2 and 7 in healing mechanism. In this book a comparative efficacy of TGF- 1, IGF-1 and the combined application of TGF- 1 and IGF-1 was evaluated in augmentation of segmental bone healing. We observed that the combined application of TGF- 1 and IGF-1 stimulated the production of osteoblasts that transformed into osteocytes produced synergistic osteoinductive effect in augmentation of fracture healing and remodeling process in combo group as compared to apply singly. I want to express my sincere wishes to Dr. S. Sarkar and Prof. Subhashis Biswas for their inspiring attitude that increased the strength for such work. Finally I want to express my sincere gratitude to my wife Sipra and son Himanish for their constant support.

Current Update on Orthobiologics in Foot and Ankle Surgery, An Issue of Clinics in Podiatric Medicine and Surgery,

Current Update on Orthobiologics in Foot and Ankle Surgery, An Issue of Clinics in Podiatric Medicine and Surgery, PDF Author: Barry Rosenblum
Publisher: Elsevier Health Sciences
ISBN: 0323342019
Category : Medical
Languages : en
Pages : 193
Book Description
Carbon-based scaffolds, bioengineered alternative tissues, and bone graft substitutes are some of the articles included in this issue. The authors discuss their uses in the patient with diabetes as well as those with elective and reconstructive foot and ankle surgery.

Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1844
Book Description


New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System –

New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System – PDF Author:
Publisher: Elsevier
ISBN: 0128045922
Category : Medical
Languages : en
Pages : 412
Book Description
New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System - Part B is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields. This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields

Transforming Growth Factor-Beta in Cancer Therapy, Volume I

Transforming Growth Factor-Beta in Cancer Therapy, Volume I PDF Author: Sonia B. Jakowlew
Publisher: Springer Science & Business Media
ISBN: 1597452920
Category : Medical
Languages : en
Pages : 735
Book Description
Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. This volume’s companion, Cancer Treatment in Therapy, examines transforming growth factor- ß in other developing and advanced cancers and methods of treatment and therapy.

Cornea, E-Book

Cornea, E-Book PDF Author: Mark J Mannis
Publisher: Elsevier Health Sciences
ISBN: 0323674720
Category : Medical
Languages : en
Pages : 1976
Book Description
The only reference available that synthesizes this vast subspecialty into a single trustworthy resource, Cornea, 5th Edition, provides state-of-the-art coverage of the expanding range of contemporary corneal surgery, new diagnostic and imaging technologies, and medical management of corneal and external disease as well as ocular surface disease. Drs. Mark J. Mannis, Edward J. Holland, and a team of more than 200 global experts keep you up to date with both common and more obscure diseases and disorders and the best route to effective treatment and management, making this two-volume text a must-have resource for residents and fellows, general ophthalmologists, and seasoned cornea specialists. Features more than 2,300 exceptionally clear illustrations, diagnostic images, and step-by-step surgical photographs that offer superb visual guidance. Contains 14 new chapters, including Nanothin DSAEK, Aqueous Deficiency Dry Eye Syndrome, Evaluation of Recurrent Corneal Erosions, Evaluation of the Corneal Ulcer, Contemporary Approaches to the Biosynthetic Cornea, and Topography Guided Photorefractive Keratectomy, and more. Includes more than 80 video clips of current corneal surgery techniques, including new clips of the application of cryopreserved amniotic membrane in the treatment of acute stevens , penetrating keratoplasty, DM rupture management in STALK and in the keratonconus patient, and KAMRA corneal inlay implantation. Covers the latest developments in ocular surface transplantation, including new chapters on Conjunctival Limbal Autograft (CLAU); Living Related Conjunctival Limbal Allograft (Lr-CLAL); Keratolimbal Allograft; Cultivated Limbal Epithelial Transplantation; Simple Limbal Epithelial Transplantation; and Outcomes of Ocular Surface Transplantation. Provides key point overviews in each chapter that offer easier access to crucial information.

Current Opinions in the Kyoto Cornea Club

Current Opinions in the Kyoto Cornea Club PDF Author: Kyoto Cornea Club. Meeting 1997
Publisher: Kugler Publications
ISBN: 9789062991693
Category : Cornea
Languages : en
Pages : 125
Book Description


Ocular Therapeutics

Ocular Therapeutics PDF Author: Thomas Yorio
Publisher: Academic Press
ISBN: 9780080556772
Category : Science
Languages : en
Pages : 536
Book Description
Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future. * Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. * Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases. * Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway. * New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States

The Growth Hormone/Insulin-Like Growth Factor Axis during Development

The Growth Hormone/Insulin-Like Growth Factor Axis during Development PDF Author: Isabel Varela-Nieto
Publisher: Springer Science & Business Media
ISBN: 0387262741
Category : Medical
Languages : en
Pages : 422
Book Description
Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.

Bioactive Materials for Bone Regeneration

Bioactive Materials for Bone Regeneration PDF Author: Jiang Chang
Publisher: Academic Press
ISBN: 0128135042
Category : Technology & Engineering
Languages : en
Pages : 248
Book Description
Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments